| Double-blind controlled clinical trial of oral S-adenosylmethionine versus piroxicam in knee osteoarthritis |
| Authors |
Maccagno A, Di Giorgio EE, Caston OL, Sagasta CL |
| Journal |
Am J Med 1987;83 (5A):72-77 |
| Comparator |
Piroxicam 20 mg/day |
| # subjects |
45 (completed study) |
| # on SAM-e |
22 (completed study) |
| Dose |
1200 mg/day |
| Duration |
84 days |
| End results |
- No significant difference in efficacy between SAM-e and piroxicam
- SAM-e-treated patients maintained clinical improvement longer after treatment than piroxicam-treated patients
|
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