| A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis |
| Author |
Konig B |
| Journal |
Am J Med 1987;83 (5A):89-94 |
| # subjects |
108 |
| Dose |
600 mg/day for 2 weeks; 400 mg/day for 50 weeks |
| Duration |
24 months |
| End results |
- SAM-e achieved good clinical effectiveness
- SAM-e was well tolerated
- No side effects were reported during the last 6 months of the trial
- OA-associated depressive feelings were improved
|
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