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Double-blind clinical trial of S-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis
Author Muller-Fassbender H
Journal Am J Med 1987;83 (5A):81-83
Comparator Ibuprofen 1200 mg/day
# subjects 36
# on SAM-e 18
Dose 1200 mg/day
Duration 4 weeks
End results
  • Assessed for morning stiffness, pain at rest, pain on motion, crepitus, swelling, and limitation of motion, SAMe-treated patients improved to the same extent as ibuprofen-treated patients
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