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S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies
Author Bressa GM
Journal Acta Neurol Scand Suppl 1994;154(suppl):7-14
Type of Study Meta-analysis
Studies examined  
Comparators Placebo, standard tricyclics
End results
  • Greater response rate with SAM-e than placebo
  • Response rate with SAM-e comparable to tricyclic antidepressants
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